مقایسه تأثیر ده هفته تمرین هوازی با شدت بالا و متوسط بر مقادیر پلاسمایی ICAM-I و VCAM-I در پسران چاق 13 تا 15 سال

نوع مقاله: مقاله پژوهشی

نویسندگان

1 گروه فیزیولوژی ورزشی، دانشکده ادبیات، علوم انسانی و اجتماعی، واحد علوم تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران.

2 گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران.

10.22037/jrm.2020.113867.2450

چکیده

اهداف: بیان مولکول‌های چسبان مانند مولکول چسبان بین سلولی-1 (ICAM-I) و مولکول چسبان عروقی-1 (VCAM-I) در افراد چاق می‌تواند باعث افزایش بروز آترواسکلروز و بیماری‌های قلبی شود. هدف مطالعه حاضر مقایسه ده هفته تمرین هوازی با شدت بالا و متوسط بر مقادیر پلاسمایی ICAM-I و VCAM-I پسران چاق بود.
مواد و روش‌ها: جامعه آماری پژوهش حاضر، دانش‌آموزان پسر چاق با دامنه سنی 13 تا 15 سال شهرستان بهارستان هستند. نمونه آماری تحقیق حاضر شامل 36 دانش‌آموز پسر چاق (با میانگین سنی 0/69±13/4، قد 7/88±163/06 سانتی‌متر و وزن 8/42±85/72 کیلوگرم) بود که به ‌صورت تصادفی به سه گروه شامل آزمایش با شدت بالا (دوازده نفر)، آزمایش با شدت متوسط (دوازده نفر) و گروه کنترل (بدون آزمایش) (دوازده نفر) تقسیم شدند. برنامه آزمایشی شامل ده هفته با شدت 50 تا 65 درصد (شدت متوسط) و 70 تا 85 درصد حداکثر ضربان قلب (شدت بالا)، سه جلسه در هفته اجرا شد. نمونه‌های خونی 48 ساعت قبل و بعد از آخرین جلسه آزمایش جمع‌آوری شد. ICAM-I و VCAM-I به روش الایزا سنجیده شد. تجزیه ‌و ‌تحلیل داده‌ها با استفاده از نرم‌افزار SPSS نسخه 18 و آزمون واریانس دوطرفه با اندازه‌گیری دوراهه انجام شد.
یافته‌ها: نتایج نشان داد درصد چربی بدن و وزن به دنبال تمرین با شدت بالا و متوسط کاهش معناداری داشت (05/p <0). حداکثر اکسیژن مصرفی به دنبال تمرین ورزشی افزایش معناداری داشت (05/p <0). مقادیر پلاسمایی ICAM-I در گروه آزمایش با شدت بالا در مقایسه با آزمایش با شدت متوسط کاهش معناداری مشاهده نشد. مقادیر پلاسمایی VCAM-I کاهش معناداری در گروه آزمایش با شدت بالا در مقایسه با گروه آزمایش با شدت متوسط و کنترل داشت (05/p <0).
نتیجه‌گیری: به نظر می‌رسد شدت تمرین ورزشی از راه کاهش وزن و شاخص توده بدنی و افزایش حداکثر اکسیژن مصرفی به کاهش مقادیر پلاسمایی ICAM-I و VCAM-I منجر شد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Comparing the Effect of a 10-Week High- and Moderate-Intensity Aerobic Exercise on Plasma ICAM-I and VCAM-I Levels in Obese boys

نویسندگان [English]

  • Farshad Ghazaliyan 1
  • Rahman Soori 2
  • Hosein Abednazari 1
  • Mandana Gholami 1
  • Raziyeh Mohammad Shirazi 1
1 Department of Exercise Physiology, Faculty of Lecture, Human and Social Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
2 Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tehran, Tehran, Iran.
چکیده [English]

Background and Aims: The expression of adhesion molecule such as the intercellular adhesion molecule- I (ICAM-I) and vascular adhesion molecule- I (VCAM-I) in obese people may increase atherosclerosis phenomena and cardiovascular diseases. The purpose of the current study was to investigate the effects of 10-week high-intensity and moderate-intensity aerobic trainings on plasma levels of ICAM-I and VCAM-I in obese boys.
Methods: The statistical population of the present study was obese boys of Baharestan city. The sample included 36 obese student boys aged 13.4±0.69 years old, height: 163.06±7.88 cm; weight; 85.72±8.42 kg) who were randomly assigned to three groups: high-intensity training (n=‌12), moderate-intensity training (n=‌12), and control (n=12). The training was performed at 50%-65% maximal heart rate (moderate-intensity training group) and 70%-85% maximal heart rate (high-intensity training group), three days per week for 10 weeks. The blood sample was collected 48 h before and 48 h after the last session of exercise training. The ICAM-I and VCAM-I were measured via ELISA. Data were analyzed using two-way repeated ANOVA in SPPS, version 18.
Results: The results indicated that body weight and BMI decreased significantly after moderate- and high-intensity training (p < 0.05). VO2max value significantly increased following 10 weeks of exercise training in both groups. No significant different was observed between exercise groups for plasma levels of ICAM-I. Moreover, the plasma levels of VCAM-I decreased significantly in the high-intensity training compared to the moderate-intensity training and control groups (p < 0.05).
Conclusion: It seems that intensity of training may decrease plasma levels of ICAM-I and VCAM-I through decrease of body weight and BMI and increase of VO2max.

کلیدواژه‌ها [English]

  • high-intensity training
  • Obesity
  • adhesion molecule
  • student’s boys
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