تاثیر تحریک الکتریکی مستقیم فراجمجمه ای بر پاسخ دهی اجتماعی در کودکان مبتلا به طیف اتیسم

نوع مقاله: مقاله پژوهشی

نویسندگان

1 موسسه آموزش عالی علوم شناختی، تهران، ایران گروه کاردرمانی، دانشکده علوم توانبخشی، دانشگاه علوم پزشکی شهید بهشتی، تهران،ایران

2 موسسه آموزش عالی علوم شناختی،تهران،ایران مرکز تحقیقات علوم شناختی و رفتاری،دانشگاه علوم پزشکی تهران،ایران

3 کلینیک مغز و شناخت، تهران، ایران

4 مرکز تحقیقات سلولی مولوکولی غدد علوم پزشکی شهید بهشتی، تهران، ایران

10.22037/jrm.2020.113989.2472

چکیده

مقدمه و اهداف
هدف از پژوهش حاضر بررسی تاثیر تحریک مستقیم فراجمجمه ­ای بر پاسخ­دهی اجتماعی در کودکان مبتلا به اختلال طیف اتیسم بود.
مواد و روش­ ها
24 کودک مبتلا به اختلال طیف اتیسم با عملکرد بالا با استفاده از نمونه­ گیری در دسترس انتخاب شدند که از نظر هوش کلامی همسان بودند و به ­طور تصادفی در دو گروه آزمایش و کنترل قرار گرفتند، قبل و بعد از تحریک ارزیابی با استفاده از ویرایش دوم آزمون Gilliam Autism Rating Scale که شامل چهار خرده‌­مقیاس رفتارهای کلیشه‌ای، برقراری ارتباط، تعاملات اجتماعی و اختلالات رشدی و پرسشنامه Social Responsiveness Scale جهت بررسی پاسخ­ های اجتماعی کودکان طیف اتیسم انجام گرفت و با هم مورد مقایسه قرار گرفته و نتایج حاصله گزارش گردید. پروتکل مورد استفاده تحریک الکتریکی مستقیم با شدت جریان 2 میلی­آمپر به مدت 20 دقیقه برای 5 جلسه متوالی و جاگذاری الکترود آند بر پشتی خلفی پیش ­پیشانی چپ و الکترود کاتد روی بازوی راست انجام گردید.
یافته ­ها
تحلیل داده­ ها تفاوت معناداری بین دو گروه در پیش ­آزمون و پس­ آزمون را نشان داد که کاهش علائم اتیسم (P=(0/002)-F(1-22)) و بهبود پاسخ ­دهی اجتماعی  (P=(0/014)-F(1-22))است.
نتیجه­ گیری
به نظر می­رسد که استفاده از  تحریک مستقیم فراجمجمه ­ای می­تواند ابزار کلینیکی مفیدی در بهبود ارتباط اجتماعی و پاسخ­ دهی اجتماعی در کودکان مبتلا به اختلال طیف اتیسم باشد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Evaluation of One-Blind Clinical Trial, Direct Transcranial Direct Current Stimulation on Social Response in Children with Autism Spectrum Disorder

نویسندگان [English]

  • Ashkan Irani 1
  • mahdi tehranidoost 2
  • Anahita Khorami Banaraki 3
  • mahdi akbarzadeh 4
1 Department of occupatinaltherapy, school of rehabilitation , shahid Beheshti University of Medical Science, Tehran, Iran
2 Institute for Cognitive Science studies, tehran, iran
3 Brain and cognition Clinic
4 Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Background and Aims: The present study aimed to investigate the effect of transcranial direct current stimulation on social response in children with autism spectrum disorder.
Materials and Methods: A total of 24 children (Mage: 10.79±3.22) with high-functioning autism spectrum disorder were selected using convenience sampling method and randomly divided into two experimental and control groups, which were matched in verbal IQ. Symptoms of autism and social response were assessed using Gilliam Autism Rating Scale and social responsiveness scale questionnaires before and after transcranial direct current stimulation. The protocol used was transcranial direct current stimulation with a current of 2 mA for 20 minutes for 5 consecutive sessions with the placement of the left dorso latral prefrontal anode electrode and the cathode electrode on the right arm.
Results: Data analysis showed a significant difference between the two groups in reducing autism symptoms (P=(0/002)-F(1-22)) and improving social response in pre-test and post-test (P=(0/014)-F(1-22)).
Conclusion: It seems that the use of transcranial direct current stimulation can be a useful clinical tool in improving social communication and social response in children with autism spectrum disorder.

کلیدواژه‌ها [English]

  • Autism Spectrum Disorder
  • Social communication
  • Transcranial current direct stimulation
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