نوع مقاله : مقاله مروری
نویسندگان
1 عضو هیئت علمی گروه شنوایی شناسی، مرکز تحقیقات توانبخشی، دانشکده علوم توانبخشی، دانشگاه علوم پزشکی ایران، تهران، ایران
2 عضو هیئت علمی گروه شنواییشناسی، مرکز تحقیقات توانبخشی عضلانی-اسکلتی، دانشگاه علوم پزشکی جندی شاپور اهواز، دانشجوی دکتری شنوایی شناسی دانشگاه علوم پزشکی تهران، تهران، ایران
3 دانشجوی دکتری دپارتمان مهندسی گاز، دانشگاه صنعت نفت، اهواز، ایران
4 عضو هیئت علمی گروه شنوایی شناسی، مرکز تحقیقات توانبخشی عضلانی-اسکلتی، دانشگاه علوم پزشکی جندی شاپور اهواز، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background and Aims: One of the major causes of sensorineural hearing loss is Noise-induced hearing loss. Cochlear damage following noise exposure occurs through two major mechanisms: direct mechanical damage and biochemical pathways. Direct mechanical damage causes hair cell loss through mechanical damage of sterreocilia and direct damage of sensory and protective cells. Cochlear damage following noise exposure through biochemical pathway result in cell death through apoptosis or necrosis. The reason for this is Oxidative Stress and generation of reactive oxygen species following noise exposure. This may remain in the cochlea long after noise exposure has been terminated.
Materials and Methods: In order to review the relationship between Cell death, Oxidative Stress and Noise induce hearing loss, all of the articles in this field published between 1990-2017 in Ovid, ProQuest, and Google Scholar databases were searched.
Conclusion: This fact shows the importance of preventing apoptosis even after exposure to noise. Understanding noise-induced cochlear damage, especially the importance of free radical expression in the cochlea, can lead to advancements in preserving the hearing.
کلیدواژهها [English]
10. Wahlqvist ML. Antioxidant relevance to human health. Asia Pac J Clin Nutr. 2013;22(2):171-6. Review. ##
11. Seidman MD, Shivapuja BG, Quirk WS. The protective effects of allopurinol and superoxide dismutase on noise-induced cochlear damage. Otolaryngol Head Neck Surg. 1993;109(6):1052-6. ##
12. Franzé A, Sequino L, Saulino C, Attanasio G, Marciano E. Effect over time of allopurinol on noise-induced hearing loss in guinea pigs. Int J Audiol. 2003;42(4):227-34. ##
13. Minami SB, Yamashita D, Ogawa K, Schacht J, Miller JM. Creatine and tempol attenuate noise-induced hearing loss. Brain Res. 2007;1148:83-9. ##
14. Le Prell CG, Hughes LF, Miller JM. Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma. Free Radic Biol Med. 2007;42(9):1454-63. ##
15. Yildirim I, Kilinc M, Okur E, Inanc Tolun F, Kiliç MA, Kurutas EB, Ekerbiçer HC. The effects of noise on hearing and oxidative stress in textile workers. Ind Health. 2007;45(6):743-9. ##
16. Quaranta N, Dicorato A, Matera V, D'Elia A, Quaranta A. The effect of alpha-lipoic acid on temporary threshold shift in humans: a preliminary study. Acta Otorhinolaryngol Ital. 2012;32(6):380-5. ##
17. Le Prell CG, Johnson AC, Lindblad AC, Skjönsberg A, Ulfendahl M, Guire K, Green GE, Campbell KC, Miller JM. Increased vitamin plasma levels in Swedish military personnel treated with nutrients prior to automatic weapon training. Noise Health. 2011;13(55):432-43. ##
18. Lindblad AC, Rosenhall U, Olofsson A, Hagerman B. The efficacy of N-acetylcysteine to protect the human cochlea from subclinical hearing loss caused by impulse noise: a controlled trial. Noise Health. 2011;13(55):392-401. ##
19. Darrat I, Ahmad N, Seidman K, Seidman MD. Auditory research involving antioxidants. Curr Opin Otolaryngol Head Neck Surg. 2007;15(5):358-63. ##
20. Xiong M, He Q, Lai H, Huang W, Wang L, Yang C, Wang J. Radix Astragali injection enhances recovery from acute acoustic trauma. Acta Otolaryngol. 2011;131(10):1069-73. ##
21. Lin CY, Wu JL, Shih TS, Tsai PJ, Sun YM, Ma MC, Guo YL. N-Acetyl-cysteine against noise-induced temporary threshold shift in male workers. Hear Res. 2010;269(1-2):42-7. ##
22. Lynch ED, Kil J.Compounds for the prevention and treatment of noise-induced hearing loss. Drug Discov Today. 2005;10(19):1291-8. Review. ##