Occupational therapy in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a case report

Document Type : Case Report

Authors

1 Department of Occupational Therapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 . Student Research Committee, Department of Occupational Therapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran

10.22037/sjrm.2025.117411.3338

Abstract

Background and Aim: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare inflammatory disease that affects the central nervous system, wherein the immune system attacks the myelin sheaths in the optic nerves, brain, and spinal cord. This condition can lead to a range of symptoms, including vision loss, muscle weakness, stiffness or paralysis, confusion, seizures, and headaches. Despite the availability of medical and pharmaceutical treatments, occupational therapy with a comprehensive and holistic approach is considered the most effective option for rehabilitation because both the physical and mental areas are involved in this syndrome.

Case report:

In this study, a 7-year-old boy diagnosed with MOGAD syndrome who received occupational therapy services was presented. He was referred to the occupational therapy clinic after being hospitalized and diagnosed with MOGAD. After receiving occupational therapy interventions including neurodevelopmental therapies (Levitt and Bobath techniques), splinting and assistive devices for one year, improvement was achieved in various areas including muscle tone, fine and gross motor development, balance and ADL. In order to assess the child's condition and follow up during this period, specialized tools and tests (PEDI, Ashworth, developmental milestones, muscle shortening test, etc.) were used to measure different areas and dimensions

Conclusion:

Occupational therapy played a pivotal role in the functional recovery of this child with MOGAD. Future research is recommended to explore long-term outcomes and develop standardized protocols for rehabilitation in children with this rare condition.

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Articles in Press, Accepted Manuscript
Available Online from 12 May 2025
  • Receive Date: 05 February 2025
  • Revise Date: 23 April 2025
  • Accept Date: 12 May 2025
  • First Publish Date: 12 May 2025