Effects of Nonlinear Resistance Training on Liver Biochemical Marker Levels in Postmenopausal Women with Nonalcoholic Fatty Liver Disease

Document Type : Original article

Authors

1 PhD Student of Department of Exercise Physiology, Faculty of Physical Education, Central Tehran Branch, Islamic Azad University,Tehran, Iran.

2 Professor of Department of Exercise Physiology, Faculty of Physical Education, Central Tehran Branch, Islamic Azad University,Tehran, Iran.

3 Assistant Professor of Department of Exercise Physiology, Faculty of Physical Education, Central Tehran Branch, Islamic Azad University,Tehran, Iran.

Abstract

Background and Aim: Menopause transition is accompanied with undesirable changes in body composition, fat distribution, increased visceral fat, and prevalence of nonalcoholic fatty liver disease. But limited studies have examined the effects of physical activity on liver function in post-menopausal climacteric. The purpose of the current study was to investigate the effects of nonlinear resistance training on levels of alanine aminotransfrase, aspartate aminotransfrase, alkaline phosphatase, Gamma-glutamyl transferase, total bilirubin, and platelet count in post-menopausal women with obesity and nonalcoholic fatty liver disease.
Materials and Methods: A total of 23 post-menopausal women with non-alcoholic fatty liver disease, between 60 to 71 years old, were randomly assigned to resistance training (n=12) and control (n=11) groups. The experimental group received 12-weeks of the resistance training with different intensities and the participants in control group continued their normal sedentary life. Blood samples were obtained before and after the protocol. Data was analyzed running one-way ANCOVA and paired t test using SPSS (version 22) (p<0.05).
Results: Alanine aminotransfrase (p=0.013) and aspartate aminotransferase (p=0.000) levels significantly decreased in resistance training group but not in control group (p>0.05). Alkaline phosphatase, Gamma-glutamyl transferase, total bilirubin, and platelet counts did not significantly change in the two groups (p>0.05), while muscle strength was improved in resistance training group (p=0.000).
Conclusion: The results showed that with aging, menopausal transition, inactivity, weight gaining, and prevalence of non-alcoholic fatty liver disease were evident. These factors would endanger the health of post-menopausal women. But nonlinear resistance training is helpful to improve liver function and muscle strength. These findings can be helpful for physicians, coaches, and designers of training plans to reduce the side effects of drug therapy.
 
 

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Main Subjects


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Volume 5, Issue 4
January and February 2017
Pages 136-145
  • Receive Date: 24 November 2015
  • Revise Date: 23 February 2016
  • Accept Date: 05 March 2016
  • First Publish Date: 21 December 2016